The effect of Levitra on kidney function in rabbits with induced Diabetes
Start
STUDY OBJECTIVES
A pilot study of the effect of Levitra on kidney function in rabbits with induced Diabetes.
METHODS
Blood and urine samples were analysed from two groups: a group of rabbits with induced diabetes given Levitra and a control group.
RESULTS
Serum creatinine concentration significantly increased after six months Diabetes, was significantly reduced by Levitra. As compared to control animals, TP/C from diabetic rabbit spot urine samples at six months were elevated significantly, demonstrating that proteinuria was present. TP/C was also normalised. Diabetic animals receiving Levitra showed a significant improvement in CrCl when compared with diabetic animals given vehicle.
CONCLUSION
There is a potential role for Levitra in the treatment of kidney damage caused by long-term exposure to high blood glucose levels.
Further reports
A short research exercise has recently confirmed that the Erection Quality Scale is responsive and internally consistent, and more useful than the International Index of Erectile Function. This study provides strong evidence supporting the use of the Erection Quality Scale in clinical trials. It was assumed that sexual symptoms can be evidence of underlying disease. Thus, sexual enquiry should be an integral component of diagnostic methodology.
A number of other research trials are under way to assess the evidence of effectiveness and safety over time. One of the most important is the investigation of the appearance of vision problems in a very small number of users. Other than this, the PDE5 inhibitors are mature products in a well-established market so the focus of research is shifting to measure other factors.